After receiving a cortisone injection, any patient who suspects an infection or runs a fever is advised to contact their doctor. People who are more prone to infection, such as those who have autoimmune diseases and who take immune-suppressing medications, should inform their health care provider. Though rare, 7, 8 infection is a serious potential side effect. The same study did not find an association with increased knee pain. For example, one study 6 found an association between repeated cortisone injections and 0.11 cm loss of cartilage in the knee. Research suggests cortisone injections may have a negative effect on cartilage. Patients can reduce their risk of tendon injuries by resting the affected joint for a few days after the injection and then gradually increasing activity with recommended stretching and exercises. 5 Because of this risk, physicians take precautions to avoid placing a cortisone injection in or directly next to a tendon. What to Know Before Getting a Cortisone InjectionĬortisone Injection Risks and Side EffectsĬortisone injections can weaken nearby tendons and make them more prone to tearing.Cortisone Injections (Steroid Injections).This side effect occurs in 1.3% to 4% of patients 3 and seems to be related to the type and concentration of corticosteroid medication used. #Side effect of cortisone shots in knees skin#2 Skin discoloration is not harmful to patients' health. Skin discoloration may last a few weeks or months or be permanent. 1, 2 This side effect is most common in darker-skinned patients, who notice the skin becomes lighter. Patients may notice the skin around the injection site changes color a few weeks or months after the injection. See When and Why to Apply Cold to an Arthritic Joint Skin Discoloration A flare typically lasts one or two days and can be treated with rest and intermittent cold packs. This side effect is called a cortisone flare. The crystals can cause pain and inflammation that is worse than the pain and inflammation caused by the condition being treated. The injected cortisone medication can crystallize inside the body. Potential risks and side effects include: Pain and Swelling (Cortisone Flare) Patients are advised to discuss concerns about risks and side effects with their health care providers before receiving cortisone injections. Most are mild or temporary, but some can be serious or long-lasting. Like any treatment, these injections carry certain risks and side effects. Arthritis and other joint problems may be treated with cortisone injections.
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